Food Sensitivity Complete™ Pathway

Wheat Reactivity • Cross-Reactive Foods • Comprehensive Food Immune Responses
A targeted immune-informed approach to wheat sensitivity and gut barrier dysfunction.

(U.S. exclusive)

Overview

Food sensitivity testing is most clinically useful when immune responses are interpreted in context and not in isolation.

Food Sensitivity Complete™ combines three complementary Cyrex panels to assess:

  • Primary immune reactivity to wheat, including processed forms
  • Gluten-associated cross-reactive foods
  • Broader immune responses to foods as they are commonly consumed

Together, these panels provide a layered immune view of food-driven inflammation, helping clinicians distinguish core immune triggers from secondary or amplifying responses and build clearer dietary strategies with confidence.

Why Food Sensitivity Complete™

Patients with food-related symptoms rarely react to foods in isolation or only in their raw form.

Modern diets include foods that are:

  • Cooked
  • Processed
  • Modified through fermentation, heating, or industrial preparation

Immune responses may differ significantly depending on how a food is prepared.

  • Identify foundational immune triggers (such as wheat)
  • Recognize cross-reactive or amplifying foods
  • Interpret broader immune engagement across foods in real-world dietary forms
  • Avoid unnecessary over-restriction driven by incomplete testing

What's Included with Food Sensitivity Complete™ Pathway

WheatBurden™

Immune Reactivity to Wheat, Gluten, and Their Processed Protein Forms
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Array 4

Gluten-Associated Cross-Reactive Foods & Food Sensitivity™
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Array 10

Multiple Food Immune Reactivity Screen™
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WheatBurden™ (Formerly Array 3X)

Immune Reactivity to Wheat, Gluten, and Their Processed Protein Forms

Detects immune reactivity to the full spectrum of wheat and gluten proteins, including processed wheat protein forms commonly consumed in real-world diets.

This expanded approach reflects how wheat exposure actually occurs and not just as raw flour or isolated gluten fractions.

What It Measures:

  • Multiple gliadins and glutenins
  • Wheat germ agglutinin (WGA)
  • Wheat albumins and globulins
  • Native and deamidated gliadin peptides
  • Gliadin–transglutaminase complexes
  • Microbial and tissue transglutaminases
  • Immune responses to processed wheat products (e.g., breads, doughs, pasta)

Helps determine whether wheat is a primary immune driver contributing to broader food sensitivity patterns.

Array 4

Gluten-Associated Cross-Reactive Foods & Food Sensitivity™

Evaluates immune reactivity to foods and food proteins known to cross-react with gluten or delay clinical improvement in gluten-reactive individuals.

What It Measures:

Immune responses to a curated list of foods with known structural similarity or co-reactivity potential, including:

  • Casein, whey
  • Corn, rice, oats
  • Coffee proteins
  • Yeast
  • Millet, buckwheat, quinoa
  • Sesame, potato, amaranth, tapioca

Array 4 helps explain why symptoms may persist even after gluten removal.

Array 10

Multiple Food Immune Reactivity Screen™

Provides a comprehensive assessment of immune reactivity across 180 foods, measured in raw, cooked, and modified forms to better reflect real-world dietary exposure.

Rather than focusing on isolated ingredients, Array 10 supports interpretation of patterns of immune engagement across commonly consumed foods.

Key Food Categories Include:

  • Animal and plant proteins
  • Grains and starches
  • Fruits and vegetables
  • Nuts and seeds
  • Dairy and eggs
  • Herbs, spices, and food additives

Designed to support dietary rotation, prioritization, and tolerance-focused planning, not blanket elimination.

Clinical Application

Food Sensitivity Complete™ is designed for providers managing patients with complex, unclear, or persistent food-related symptoms.

Ideal for patients with:

  • Multiple food reactions without clear patterns
  • Symptoms that persist despite elimination diets
  • Autoimmune or inflammatory presentations with dietary triggers
  • GI, neurologic, dermatologic, or systemic symptoms linked to food intake
  • Prior food sensitivity results that lacked context or clinical direction

How to use Food Sensitivity Complete™ in Practice

  1. Identify foundational triggers. WheatBurden™ clarifies whether wheat, especially its processed forms, are driving immune activation.
  2. Address immune amplification. Array 4 identifies cross-reactive foods that may sustain symptoms even after gluten removal.
  3. Interpret broader immune patterns. Array 10 provides context across foods as they are actually consumed, helping differentiate primary drivers from secondary responses.
  4. Build a clearer dietary roadmap. Results support phased dietary changes, improved compliance, and more confident follow-up strategies.

    Why This Approach Works

    Food sensitivity testing that ignores food preparation can miss clinically relevant immune responses.

    Food Sensitivity Complete™ integrates immune reactivity across raw, cooked, and processed foods—offering a more realistic, actionable view of food-driven immune stress.